Different experimental set-ups were designed to study cytotoxic and cytoststic effects on HTB140 melanoma cells after 1 h treatment with fotemustine (FM) or dacarbazine (DTIC). FM induced dose dependent cell inactivation, boosted by its toxicity, particularly for higher doses. DTIC treatment for 1 h was insufficient to provoke almost any effect on melanoma cells. Good correlation between viability and proliferation assays applied was detected for both drugs.Physical chemistry 2006 : 8th international conference on fundamental and applied aspects of physical chemistry; Belgrade (Serbia); 26-29 September 200
