Background: Clustering of chronic non-communicable diseases has been described in the western world. We embarked on this study to determine spousal concordance of chronic kidney disease (CKD).Methods: A hospital based descriptive cross sectional study of spouses of patients with advanced CKD (stage 4 and 5).Results: A significantly higher prevalence of CKD was detected among spouses of patients with advanced CKD (21%) compared with (6%) in spouses of patients without CKD. Variables associated with CKD included age, hypertension, diabetes mellitus, chronic use of nonsteroidal antiinflammatory drugs and use of herbal medication (p<0.05).Conclusion: This study has shown that spouses of patients with advanced CKD are at increased risk of developing CKD.Keywords: Chronic Kidney Disease, Concordance, Diabetes Mellitus, Hypertension, Spous