Antihyperglycaemic effect of aqueous extract of Daniella oliveri and Sarcocephalus latifolius roots on key carbohydrate metabolic enzymes and glycogen in experimental diabetes
The blood sugar lowering effect of the aqueous extract of Sarcocephalus latifolius S. M. (Rubiaceae) and Daniella oliveri Rolfe (Caesalpiniaceae) roots (250mg/kg) was investigated on normoglycaemic and alloxan induced diabetic rats. In addition, hexokinase, glucokinase andphosphofructokinase activities as well as hepatic glycogen content were assessed. The extract’s potency was compared with a standard drug, glibenclamide. The test dose of the extract caused asignificant (
