Background: Uterine perforation during diagnostic hysteroscopy is relatively rare event in an experience hand. They however occur more frequently with operative hysteroscopy than with diagnostic hysteroscopy. The exact incidence differ from centre to centre depending on the indication for the procedure and the experience of the surgeon. This centre has a five year experience in diagnostic hysteroscopy, and occasionally therapeutic hysteroscopy in adhesiolysis and retrieval of missing intrauterine contraceptive device.Objective: To evaluate the rate of uterine perforation during different hysteroscopic procedures, whether it can be predicted by specific patient characteristics or the indication for the hysteroscopic procedure.Study design, settings and subjects: This is a retrospective analytical study, conducted at Aminu Kano Teaching Hospital, which involved all the patients that had hysteroscopy from 2009 – 2012.Method: Case files of all patients that had diagnostic hysteroscopy in Aminu Kano Teaching Hospital, Kano, within a three year period(from 5th January, 2009 – 5th of January, 2012), were reviewed.Results: A total of 36 patients had hysteroscopy for various indications within the 3 yr study period.4 patients had uterine perforation. All the 4 patients, had hysteroscopy for Asherman's syndrome.Conclusion: The risk of uterine perforation was higher during hysteroscopy for patients with Asherman's sydrome than during other procedures. Special precaution should therefore be taken in this group of patients during hysteroscopy to avoid uterine perforation.Keywords: Incidence, uterine perforation, hysteroscopy, Asherman's syndrome