Objectives: To assess the relationship between prostate volume (PV), prostate specific antigen (PSA) and age in a cohort of Saudi men from the Urology Department, King Abdul Aziz University Hospital, Jeddah, Saudi Arabia.Methods: Medical records of 447 Saudi men aged 20-89 years with benign prostatic conditions seen between January 2003 and June 2009, were reviewed, retrospectively. Cases with PSA >10 ng/ml, proven prostate cancer, previous prostate surgery or those who received 5-alpha reductase inhibitors (5-ARIs) were excluded. The study population was categorized into seven successive age groups (20-89 years). The variables of age, PV and PSA were examined. Using mean PV of the 20-29 years age group and mean PSA of the 40-49 years age group as reference points, percentage differences in mean PV and mean PSA in subsequent age groups were determined. A p-valu
