Despite increasing safety of regional anaesthesia, the growth in the popularity therof implies that local anaesthetic toxicity will occur occasionally. Local anaesthetic cardiotoxicity, even when using “safer” modern local anaesthetics, is notoriously resistant to standard resuscitation. The aim of this paper is to review current knowledge regarding the use of lipid emulsions to treat local anaesthetic toxicity.Keywords: lipid emulsion therapy; local anaesthetic toxicity; local anaesthetic cardiotoxicity; cardiopulmonary resuscitation; bupivacaine cardiotoxicit