International Myeloma Working Group guidelines for the management of
multiple myeloma patients ineligible for standard high-dose chemotherapy
with autologous stem cell transplantation
In 2005, the first guidelines were published on the management of
patients with multiple myeloma (MM). An expert panel reviewed the
currently available literature as the basis for a set of revised and
updated consensus guidelines for the diagnosis and management of
patients with MM who are not eligible for autologous stem cell
transplantation. Here we present recommendations on the diagnosis,
treatment of newly diagnosed non-transplant-eligible patients and the
management of complications occurring during induction therapy among
these patients. These guidelines will aid the physician in daily
clinical practice and will ensure optimal care for patients with MM.
Leukemia (2009) 23, 1716-1730; doi: 10.1038/leu.2009.122; published
online 4 June 200