Photostress recovery time (PSRT) is a clinical procedure that measures the amount of time required for the macular to return to its normal level of function after being exposed to a bright light source. This study was a case control clinical study carried out to measure the foveal and extra-foveal photo stress recovery time in participants with primary open angle glaucoma. Fifty five subjects, 24 with primary open angle glaucoma with a mean age of 34.38±12.19 and 31 control subjects with a mean age of 26.58±7.23 were used in this study. The mean photostress recovery time measured on the fovea, 7o nasal, temporal, inferior and superior to the fovea were, 62.38±4.67, 8.71±7.19, 11.23±10.96, 12.08±8.96 and 12.44±9.30 respectively for subjects with primary open angle glaucoma. For the control subjects, the mean photostress recovery time measured on the fovea, 7o nasal, temporal, inferior and superior to the fovea were 23.29±1.63 11.89±8.62, 11.53±8.19, 12.89±8.67 and 13.60±8.36 respectively. Analysis with SPSS version 21 using the two factor ANOVA showed a significant difference (P<0.05) in photostress recovery time 7o nasally, temporally, inferiorly and superior to the fovea between primary open angle glaucoma subjects and a control group. Data analysis with the independent sample t-test also showed a significant difference (P<0.05) in photostress recovery time on the fovea between primary open angle glaucoma subjects and a control group. In conclusion, primary open angle glaucoma alters the photostress recovery time, both on the fovea and extra-foveal region of the retina. Photostress recovery test should be included in the routine eye examination of patients.Keywords: Primary Open angle glaucoma, Photostress recovery time, foveal, extra-fovea