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Inflammation associates with impaired small arterial elasticity early in HIV disease
Authors
T.E. Peterson Hullsiek, K.H. Engen, N.W. Kumarasamy, N. Lebech, A.-M. Liappis, A. Papadopoulos, A. Polizzotto, M.N. Schreiner, P.J. Duprez, D. Baker, J.V. INSIGHT START (Strategic Timing of AntiRetroviral Treatment) Study Group
Publication date
1 January 2018
Publisher
Abstract
We estimated small arterial elasticity and used linear regression to evaluate its association with inflammatory biomarkers among antiretroviral therapy-naïve, HIV-positive patients with high CD4+ counts. After adjustment, high-sensitivity C-reactive protein and interleukin-6 were inversely associated with small arterial elasticity. These data suggest that systemic inflammation may contribute to vascular dysfunction even in very early HIV disease. © The Author(s) 2018
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Pergamos : Unified Institutional Repository / Digital Library Platform of the National and Kapodistrian University of Athens
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oai:lib.uoa.gr:uoadl:3107331
Last time updated on 10/02/2023