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Heparin induced thrombocytopenia: Contemporary therapeutic approaches in light of the new oral anticoagulants
Authors
E.A. Sanidas Viniou, N.A. Diamantopoulos, P. Barbetseas, J.
Publication date
1 January 2015
Publisher
Abstract
Heparin induced thrombocytopenia (HIT) is a prothrombotic syndrome initiated by platelet- activating auto-antibodies with potentially devastating complications. Once the diagnosis of HIT is suspected, discontinuation of heparin and treatment with an alternative anticoagulant are mandatory. While established drugs for HIT are no longer available, parenteral factor Xa inhibitors, thrombin inhibitors and perhaps the direct oral anticoagulants provide additional treatment options. The aim of this review was to highlight the current clinical aspects regarding HIT focusing on the role of novel medications. © Schattauer 2015
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Pergamos : Unified Institutional Repository / Digital Library Platform of the National and Kapodistrian University of Athens
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oai:lib.uoa.gr:uoadl:3125368
Last time updated on 10/02/2023