The isolation and antibacterial activity of anabaena phycocyanin were investigated. The result indicates that three kinds of protein ingredients: PC-A, PC-B and PC-C were obtained using high performance liquid chromatography. The estimated molecular masses of PC-A and PC-B were 14 to 18 kD. PC-B and PC-C had certain antibacterial activity on Bibrio parahemolyticus, Bacillus mucilaginosus and Sarcina lutea. In addition, PC-C had certain antibacterial activity on Vibrio harveyi. PC-A did not possess antibacterial activity in the study.Keywords: Anabaena, phycocyanin, liquid chromatogram, antibacterialAfrican Journal of Biotechnology Vol. 12(15), pp. 1869-187
