Structural, Morphological and Cytotoxic Analysis of NixZ1-xFe2O4(x=0.00, 0.03, 0.07) Nanoparticles

Abstract

Nickel doped zinc ferrite compounds with the formula NixZn1-xFe2O4 (ZNFO) were prepared by using co-precipitation method.  The X-ray diffraction patterns confirm the synthesis of single crystalline NixZn1-xFe2O4 ferrite nanoparticles. The lattice parameter decreases whereas crystallite size increases with the increase in nickel ion concentration. The structure of nanoparticles was studied using X-ray diffraction pattern. The band gap energy for normal zinc ferrite is found to be 1.77.  Whereas the bandgap energy decreases to 1.03 eV  and 1.02 for Nix Zn1-xFe2O4 with x = 0.03 and 0.07 respectively. FTIR will help to study the functional groups present in the nanoparticles, so this technique is used for qualitative analysis of materials. The microstrain decreases as nickel ion concentration increases. The obtained results revealed that NixZn1- xFe2O4[x = 0.03] nanoparticles obtained by us in a model of actinomycetes exhibit lower cytotoxicity, which was confirmed in cytotoxic assay and with high LC50 value. From safety point of view, a careful cytotoxicity analysis of ZNFO (0.03) nanoparticles with concentration up to 50µg/mL can be used for biomedical applications