A mismatch between furniture and body characteristics can cause musculoskeletal discomfort during prolonged sitting for adult learners. Sixty-seven university learners rated their perceived discomfort and ability to focus while using four common desk chairs. A desk chair with padding and a large frame was rated significantly highest in overall comfort. Participants reported significantly increased upper back pain when using a desk chair with minimal arm support. During periods of prolonged seating, desk chairs should accommodate various sized bodies and have cushioning. Upper extremity support is also recommended