Malaria parasites occur in endemic areas such as the detection of parasites in a blood film from a febrile individual does not necessarily indicate clinical malaria, the fraction that has malaria symptoms and is attributable to malaria has been a major concern especially when symptomatic patients presume that they have malaria before confirming from laboratory test. The aim of the study is to determine the proportion of the patients that actually has malaria among the symptomatic patients. The objectives are to determine the predisposing factors that will tell us if a patient has malaria before laboratory test and a model that is clinically interpretable to describe the relationship between an outcome (malaria or no malaria) and a set of independent variables. As a result of high rate of malaria cases, there is a need to conduct research on factors influencing malaria. Logistic regression was used to analyse the secondary data collected from University of Ilorin Clinic from 1st January, 2015 to 30thJune, 2015. The attributable fraction for malaria was 49.2% and 50.8% was attributable to other diseases though they have identical symptoms. Males are 2.899 times likely to have malaria than females even after controlling for genotype. Patients of AA are 4.212 times likely to have malaria than the SS patients, patients of AS are 3.991 times likely to have malaria than the SS patients
