Topological defects in an orientation field play a vital role for controlling
the collective motion of nematic cell populations within epithelia and tissue.
In this study, we study the geometric control of the collective motion in a
nematic cell population to further explore the interplay between topology and
dynamics in active nematics. By applying spatial constraints consisting of two
or three overlapping circle boundaries, we demonstrate an ordered pairing of
half-integer topological defects in a confined cell population. The defects
facing each other can induce a contractile cellular flow at broad geometric
conditions. This robust contractile flow contributes to mechanical stimulation
while altering the cell nucleus, which may be relevant to geometry-dependent
morphogenesis.Comment: 8 pages, 5 figure