Not AvailablePhage therapy has been previously tried for
treatment of diarrhoea in calves, pigs and lambs but those
trials were conducted without any detailed information of
used phages. Here, we report isolation of a broad-spectrum
phage which showed bactericidal activity against 47.3 % of
calf diarrhoeal isolates of Escherichia coli, in vitro. The
isolated phage resembled the characteristics of Myoviridae
family and showed *97 % similarity with earlier reported
bacteriophages of sub family-Tevenvirinae, genus-T4-like
virus, based on nucleotide sequence of major head protein—
gp23 gene. The phage exhibits the potential to be
used as drug substitute tool against E. coli causing diarrhoea
in cattle in farm environments.ICA
