Review of the Latest Trends in Transplantation Immunology and its Role in Mortality Reduction

Abstract

Transplantation immunology deals with the process of moving cells, tissues, or organs, from one site to another, either within the same person or between a donor and a recipient. If an organ system fails, or becomes damaged because of disease or injury, it can be replaced with a healthy organ or tissue from a donor. The process of transplantation has become increasingly popular due to its life saving benefit. In 2015 /2016 4601 patients\u27 lives were saved or improved by an organ transplant in the United Kingdom alone. Kidney transplants are the most common organ transplant followed by liver and pancreas. However, the complexity of the immune system of humans makes the process challenging. None the less immunosuppressive regimen has been introduced to reduce rejection and life-threatening consequences associated with transplant rejection. Data support the increasing benefit of the transplantation in the reduction of mortality or individuals with life threatening conditions improving their quality of life considerably. This work aims at exploring the overall benefit of transplantation in health care especially as it pertains to the reduction of mortality rate for patients in the United States and around the world

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