Swetapradara is a common and major problem in our country of female especially reproductive age. Total patients (60) were divided into three group i.e. Gr-A, Gr- B and Gr- C with clinical features of white vaginal discharge, itching of vulva, burning pain in vagina, low back pain, general weakness.Gr-A was treated with Yoni Dhavan (Vaginal irrigation) by a compound decoction. Gr- B was treated with oral medicine by Pusyanuga Churan.Gr- C was treated with both therapies i.e., Yoni Dhavan & Oral medicine. This comparative clinical trial was conducted to evaluate the efficacy of Gr-C which were confirmed that the effectiveness was better than other groups in the management of Swetapradara. This study observe a highly significant reduction in mean scores of clinical feature and overall compliance to the treatment was excellent in the Gr-C and p value of < 0.001 was considered highly significant