Hepatitis B vaccination status of health care workers and their antiHBs titres - A cross sectional study

Abstract

Back ground: The risk from occupational exposure to HBV infection is 2-4 times higher in HCW’s. A protective vaccine with a reported efficacy of 95% is available. Yet many HCW’s in developing countries remain non vaccinated, incompletely vaccinated or if vaccinated unaware of their post vaccination anti HBs status. Estimation of protective immune response following vaccination is essential to clear the misconceptions regarding booster dose of vaccine and non responder state which prevails among the HCW’s. Objective: The present study is designed to assess the hepatitis B vaccination rates in HCW’s and their antiHBs titres. Material and methods: A cross sectional study on 87 subjects was carried out at a tertiary care hospital by testing their sera for HBsAg & anti HBs levels. Results: None of the HCW’s were found to be HBsAg positive. Vaccination rate observed was 79%. Most vaccinated were the doctors and least the paramedics. Among doctors variation within the occupational groups was noticed. More number of males and young subjects were vaccinated and protected. Only 49% of the vaccinated HCW’s were vaccine compliant and 35% of these were protected. Factors like age, sex and time since last dose of vaccine influenced the anti HBs titres. None were aware of their anti HBs titres post vaccination. Conclusion: The study group involves only a small number of HCW’s but the findings are significant. Keeping in mind the annual global hepatitis B infection rates in HCW’s in developing countries we recommend the health care authorities to strengthen the existing educational programmes on Hepattis B infection which improves the awareness levels and thereby increases the vaccine rates. Further to make essential post vaccination assessment of antiHBs titres and its documentation to clear misconceptions regarding booster dose of vaccine

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