Instituto Brasileiro de Pesquisa e Ensino em Fisiologia do Exercício
Abstract
Obesity is a type of chronic inflammatory disease (CID) which kills millions of people in the world. It is alarming in recent decades as the number of children is being diagnosed with overweight and / or obesity. Inflammatory Markers (IM) produced by various cells of our body is associated with excess body fat and other CID risk factors. It is important to identify in early age IM behavior in obese children and associate them in physical exercise programs as a CID preventive measure. Aiming to fill this gap, this literature review talk about the IM behavior of C-reactive protein (CRP), interleukin-6 (IL-6), IL-18, tumor necrosis factor-α (TNF-α) and adiponectin at rest and chronic effects of exercise . It is concluded that many IM show in our biological systems similar and different behaviors; Levels of CRP and TNF- α are elevated in obese children. The same do not occur in relation to concentration of IL-6; It were not be found studies about the expression of IL-18 in obese children at rest or engaged in regular physical exercise; levels of adiponectin are low in obese children at rest; Regular physical exercise reduces chronically levels of TNF-α, IL-6 and CRP in obese children and increase levels of adiponectin
