The dynamics of two-phase fluids are applied in fields from aerospace, automobile to industrial equipment. The two-phase microfluidic systems are widely used in the research, biochemical analysis or materials synthesis. The dynamics of droplets greatly affected the quality of the interactive manipulation between two fluidic phases. A Taylor's analogy model has been developed to describe the droplet dynamics in microchannel [1]. The aim of this study is to describe the effects of conversion factors in the analogy model on the droplet deformation of the two-phase microfluidic. The result has shown that the viscous drag coefficient, the surface tension coefficient and the two-phase viscosity one have a great impact on the droplet deformation