BackgroundPlasma rich in growth factors (PRGF) has wider use in many fields of dentistry due to its endogenous biocompatible regenerative potential i.e., their potential to stimulate and accelerate tissue healing and bone regeneration.AimsThis review shows the increasing use of PRGF technology in various fields of dentistry.Methods In the last nine years PubMed has been searched in order to find out published articles upon PRGF in dentistry and 36 papers have been included.Results PRGF technology has many advantages with positive clinical and biological outcomes in tissue healing and bone regeneration.ConclusionIn order to determine the most effective therapeutic value for patients, further research is required