Prevalensi Diabetes Melitus Pada Tuberkulosis Dan Masalah Terapi

Abstract

The incidence and prevalence of diabetes mellitus (DM) is rapidly increasing across the world. DM has been known as one of the risk factors for tuberculosis (TB). DM was seen to have a negative effect on the outcome of TB treatment. This paper is a literature review based on articles about DM and TB taken from PubMed, Google, and Mendeley published ten years behind. Screening for DM in persons with TB demonstrated that DM prevalence in TB population is high. DM prevalence in TB was about 5,4 % – 44,0 %. Diabetes mellitus is a risk factor to develop active tuberculosis (OR: 1,5 – 8,9). DM impairs the immunity of the patients and therefore DM is an independent risk factor for infections such as TB. Lack control of diabetes predisposes the patient to tuberculosis. People with diabetes are more likely to fail TB treatment compared to those without diabetes. Effective management of both diseases require the same elements including early detection, providing guided standard treatment, and proper drug intak