: Sleep/rest is one of human needs, sleep disorder such as insomnia can interfere our daily activities. In Indonesia, the prevalence reached 10% of people with insomnia, one primary causes of insomnia is smoking. In Indonesia, smoking population aged ≥ 15 years old reached up to 34,7%. This research is based on analytic survey with cross sectional analytic study. This research aimed to determine the association between insomnia with active smokers. The Population of this study is all of public transport drivers who live in Manado, North Sulawesi. Sample of this study is part of the public transport drivers with total samples 52 participants.The results showed that 23% of active smokers with insomnia. The result of chi-square test showed that there is a significant correlation (p < 0.05) between insomnia and duration of smoking (p = 0.004), insomnia and active smokers (p = 0.023). There is an association between insomnia and active smokers