There are many toxic elements of tobacco smoke, one of which is a nitrogen oxide (NOx). This study aims to determine the effect of elimination of cigarette smoke before and after using a plasma reactor and perform calculations on the efficiency of each power supply voltage variations. The study was conducted by research such as determining variables and do the research procedures. The independent variables used are variations of the electric voltage of 1 kV; 1.5 kV; and 2 kV was tested for cigarette filter types and clove cigarettes. For the independent variable is the concentration of nitrogen oxides (NOx) in cigarette smoke. For the control variables of the gas flow rate 2,2L / min and the amount of cigarettes that are used in each test are 2 . The procedure research which is conducted by cigarette burning on the inlet and suck the smoke using the handpump and running it into the gas reservoir tube to homogenized, after it flowed into the reactor and measured plasma concentrations of NOx gases contained in cigarette smoke using a gas analyzer. The results showed that plasma technology can lower the NOx concentration. With the best results obtained when using a power supply voltage of 1,5 kV at each of the various types of cigarettes