Several existing and planned facilities, worldwide, use protons at 650-2000 MeV to produce neutrons by spallation reactions. In the advanced spallation neutron sources, materials in the target and blanket structures will be exposed to high-energy proton fluences at 10{sup 25}-10{sup 26}/m{sup 2} per year. Information obtained in fusion reactor studies are being applied to the design of spallation neutron sources. The APT project is sponsoring a materials qualification program including irradiations in the proton beam and neutron field at the Los Alamos Spallation Radiation Damage Facility