Measurement of human joint motion frequently involves the use of markers to describe joint motion in a global reference frame. Results may be quite arbitrary if the reference frame is not properly chosen with respect to the joint`s rotational axis(es). In nature joint axes can exist at any orientation and location relative to an arbitrarily chosen global reference frame. An arbitrary axis is any axis that is not coincident with a reference coordinate. Calculations are made of the errors that result when joint motion occurs about an arbitrary axis in a global reference frame
