Diabetes mellitus (DM) is a frequently experienced metabolic disease with chronic features and involves numerous complications around its course, which causes severe restriction and disability in an individual's common life. It was stated that the incidence of depression is higher in diabetic patients and that diabetes is one of the risk factors in the development of depression. Depression has been shown to be correlated with poor self-management (adherence to diet and medication, physical exercise, and monitoring of blood glucose levels) and high HbA1C levels. The main intention of this article is to produce a comprehensive review of epidemiological findings, clinical attentions, and management approaches concerning depression in patients with DM
