Determination of association constants of β-cyclodextrin and β-cyclodextrin-N-succinamate with drugs by high performance liquid chromatography

Abstract

Investigation of the Hummel and Dreyer method for the estimation of stability constants by high performance liquid chromatography (HPLC) is described. Comparison of the results obtained for binding of cimetidine (2a) and 2-(p-tolyl)ethylamine (2b) to β-