68-73Autism Spectrum Disorder (ASD), a neurodevelopmental disorder, has been a bottleneck to several clinical researchers
due to data modularization, subjective analysis, and shifts in the accurate prediction of the disorder amongst the sample
population. Subjective clinical research suffers from a lengthy procedure, which is a time-consuming process. In this paper,
Sailfish Optimization (SFO), a recently developed nature-inspired meta-heuristics optimization algorithm, is being utilized
to detect ASD. The hunting methodology of sailfish inspires SFO. Classical SFO has examined the search space in only one
direction that affects its converging ability. The Random Opposition Based Learning (ROBL) strategy enhances the
exploration capacity of SFO and successfully converges the predictive model to global optima. The proposed ROBL-based
SFO (ROBL-SFO) selects relevant features from autism spectrum disorder (child and adult) datasets. According to the
results obtained, the proposed model outperforms the convergence capability and reduces local-optimal stagnation compared
to conventional SFOs