Duchenne muscular dystrophy is a severe X chromosome-linked,
muscle-wasting disease caused by lack of the protein dystrophin. The exact function of dystrophin rem to be determined. However, analysis of its interaction with a
large oligomeric protein complex at the sarcolemma and the identicaton of a structurally related protein, utrophin, is
leading to the characterization of candidate genes for other neuromuscular disorders
