The configurational approach enables understanding the behaviour of road-network systems in
the face of sudden physical disruptions. Previous studies show that Space Syntax analysis can
assist in evaluating how urban systems respond to punctual network interruptions, both in the
short and medium-term, and help managing associated risks. The events which followed the crash
of the Polcevera bridge in Genoa and that of Bologna Borgo Panigale bridge in 2018
demonstrated in practice that localised urban network interruptions can propagate, affecting
movement dynamics, well beyond the boundary of a city and compromise the functioning of the
regional motorway network. However, representing the associated effects across the urban to the
regional network levels remains a challenge due to computational limitations which constrain
Space Syntax studies to use simplified networks in their analyses. This in turn causes
discrepancies in cross-scale comparisons, as urban and regional road-morphologies are
represented at different levels of detail. The paper studies the effects of the two dramatic events
from a multi-scale configurational standpoint by comparatively analysing the through-movement
patterns of the urban road-, the regional primary- and the regional motorway- circulation systems.
The goal of this research is to discuss, using a real-world example as a benchmark for
assessment, the viability of adopting the configurational approach to study failure propagation
and gauge levels of street network resilience across spatial scales. The results of this study clarify
the importance of weak ties for the resilience of road infrastructure systems and further
demonstrate the homothetic behaviour of Normalised Betweenness Centrality measures