In the abstract Tile Assembly Model (aTAM) square tiles self-assemble,
autonomously binding via glues on their edges, to form structures. Algorithmic
aTAM systems can be designed in which the patterns of tile attachments are
forced to follow the execution of targeted algorithms. Such systems have been
proven to be computationally universal as well as intrinsically universal (IU),
a notion borrowed and adapted from cellular automata showing that a single tile
set exists which is capable of simulating all aTAM systems (FOCS 2012). The
input to an algorithmic aTAM system can be provided in a variety of ways, with
a common method being via the "seed" assembly, which is a pre-formed assembly
from which all growth propagates. In this paper we present a series of results
which investigate the the trade-offs of using seeds consisting of a single
tile, versus those containing multiple tiles. We show that arbitrary systems
with multi-tile seeds cannot be converted to functionally equivalent systems
with single-tile seeds without using a scale factor > 1. We prove tight bounds
on the scale factor required, and also present a construction which uses a
large scale factor but an optimal number of unique tile types. That
construction is then used to develop a construction that performs simultaneous
simulation of all aTAM systems in parallel, as well as to display a connection
to other tile-based self-assembly models via the notion of intrinsic
universality.Comment: To appear in the SODA 2023 proceeding