This paper deals with the issue of developing a smart vibration control platform following an innovative model‐based approach. As a matter of fact, obtaining accurate information on system response in pre‐design and design phases may reduce both computational and experimental efforts. From this perspective, a multi‐degree‐of‐freedom (MDOF) electro‐mechanical coupled system has been numerically schematized implementing a finite element formulation: a robust simulation tool integrating finite element model (FEM) features with Simulink® capabilities has been developed. Piezo strain actuation has been modelled with a 2D finite element description: the effects exerted on the structure (converse effect) have been applied as lumped loads at the piezo nodes interface. The sensing (direct effect) has instead been modelled with a 2D piezoelectric constitutive equation and experimentally validated as well. The theoretical study led to the practical development of an integrated circuit which allowed for assessing the vibration control performance. The analysis of critical parameters, description of integrated numerical models, and a discussion of experimental results are addressed step by step to get a global overview of the engineering process. The single mode control has been experimentally validated for a simple benchmark like an aluminum cantilevered beam. The piezo sensor‐actuator collocated couple has been placed according to an optimization process based on the maximum stored electrical energy. Finally, a good level of correlation has been observed between the forecasting model and the experimental application: the frequency analysis allowed for characterizing the piezo couple behavior even far from the resonance peak
