The alcohol dehydrogenase from Lactobacillus brevis (LbADH) is a versatile catalyst for enantioselective reduction of ketones. Its substrate scope is wide with high regio- and enantioselectivity. In this critical review, we have gathered the information available on the substrate scope as well as the applications reported. Quantitative information such
as productivity per catalyst, space-time yield (STY), cofactor utilisation, and stability are derived to allow comparison and assessment of practical value
