The application of music information retrieval techniques in popular music studies has great promise. In the present work, a corpus of Radiohead songs across their career from 1992 to 2017 are subjected to automated audio analysis. We examine findings from a number of granularities and perspectives, including within song and between song examination of both timbral-rhythmic and harmonic features. Chronological changes include possible career spanning effects for a band's releases such as slowing tempi and reduced brightness, and the timbral markers of Radiohead's expanding approach to instrumental resources most identified with the Kid A and Amnesiac era. We conclude with a discussion highlighting some challenges for this approach, and the potential for a field of audio file based career analysis
