The main aim of this thesis is to evaluate the clinical risk factors and imaging techniques for the diagnosis and to analyze the treatment outcomes of Ruthenium-106 plaque brachytherapy for iris and iridociliary melanomas in terms of tumor regression and its complications, survival and development of metastasis. This thesis also focuses on the differential diagnosis of iris melanomas. Understanding of these subjects can assist ophthalmologists in the diagnosis and evidence-based management of iris melanomas, therefore avoiding unnecessary treatment of an iris naevus.Higher Education Comission of Pakistan. Nelly Reef Fund, Blinden-Penning, Liden Oogheelkundig Ondersteunings Fonds (LOOF).UBL - phd migration 201
