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Cancer incidence, mortality, years of life lost, years lived with disability, and disability-adjusted life years for 29 cancer groups from 2010 to 2019 a systematic analysis for the global burden of disease study 2019
Authors
Emad Ababneh
Mohsen Abbasi-Kangevari
+30 more
Hedayat Abbastabar
Sherief M Abd-Elsalam
Amir Abdoli
Aidin Abedi
Hassan Abidi
Hassan Abolhassani
Isaac Akinkunmi Adedeji
Qorinah Estiningtyas Adnani
Shailesh M Advani
Muhammad Sohail Afzal
Mohammad Aghaali
Bright Opoku Ahinkorah
Sajjad Ahmad
Tauseef Ahmad
Ali Ahmadi
Sepideh Ahmadi
Tarik Ahmed Rashid
Yusra Ahmed Salih
Gizachew Taddesse Akalu
Kelly Compton
Frances E Dean
Weijia Fu
Brian L Gaw
James D Harvey
Hannah Jacqueline Henrikson
Jonathan M Kocarnik
Dan Lu
Fix Me
Alyssa Pennini
Rixing Xu
Publication date
1 January 2022
Publisher
'American Medical Association (AMA)'
Doi
Cite
Abstract
IMPORTANCE The Global Burden of Diseases, Injuries, and Risk Factors Study 2019 (GBD 2019) provided systematic estimates of incidence, morbidity, and mortality to inform local and international efforts toward reducing cancer burden. OBJECTIVE To estimate cancer burden and trends globally for 204 countries and territories and by Sociodemographic Index (SDI) quintiles from 2010 to 2019. EVIDENCE REVIEW The GBD 2019 estimation methods were used to describe cancer incidence, mortality, years lived with disability, years of life lost, and disability-adjusted life years (DALYs) in 2019 and over the past decade. Estimates are also provided by quintiles of the SDI, a composite measure of educational attainment, income per capita, and total fertility rate for those younger than 25 years. Estimates include 95% uncertainty intervals (UIs). FINDINGS In 2019, there were an estimated 23.6 million (95% UI, 22.2-24.9 million) new cancer cases (17.2 million when excluding nonmelanoma skin cancer) and 10.0 million (95% UI, 9.36-10.6 million) cancer deaths globally, with an estimated 250 million (235-264 million) DALYs due to cancer. Since 2010, these represented a 26.3% (95% UI, 20.3%-32.3%) increase in new cases, a 20.9% (95% UI, 14.2%-27.6%) increase in deaths, and a 16.0% (95% UI, 9.3%-22.8%) increase in DALYs. Among 22 groups of diseases and injuries in the GBD 2019 study, cancer was second only to cardiovascular diseases for the number of deaths, years of life lost, and DALYs globally in 2019. Cancer burden differed across SDI quintiles. The proportion of years lived with disability that contributed to DALYs increased with SDI, ranging from 1.4% (1.1%-1.8%) in the low SDI quintile to 5.7% (4.2%-7.1%) in the high SDI quintile. While the high SDI quintile had the highest number of new cases in 2019, the middle SDI quintile had the highest number of cancer deaths and DALYs. From 2010 to 2019, the largest percentage increase in the numbers of cases and deaths occurred in the low and low-middle SDI quintiles. CONCLUSIONS AND RELEVANCE The results of this systematic analysis suggest that the global burden of cancer is substantial and growing, with burden differing by SDI. These results provide comprehensive and comparable estimates that can potentially inform efforts toward equitable cancer control around the world. © 2022 American Medical Association. All rights reserved. **Please note that there are multiple authors for this article therefore only the name of the first 30 including Federation University Australia affiliate “Muhammad Aziz Rahman" is provided in this record*
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vital:16780
Last time updated on 02/12/2022
Scholar Commons - Institutional Repository of the University of South Carolina
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Last time updated on 16/07/2023