Geva, Tal

Greil, Gerald

Lamata, Pablo

Razavi, Reza

Wong, James

Zacur, Ernesto

Ernesto Zacur

James Wong

Reza Razavi

Tal Geva

Gerald Greil

Pablo Lamata

Crossref

Revealing Differences in Anatomical Remodelling of the Systemic Right Ventricle

Cardiac remodelling, which refers to the change of the shape and size of the myocardium, is an adaptive response to developmental, disease and surgical processes. Traditional metrics of length, volume, aspect ratio or wall thickness are used in the clinic and in medical research, but have limited capabilities to describe complex structures such as the shape of cardiac ventricles. In this work we present an example of how computational analysis of cardiac anatomy can reveal more detailed description of developmental and remodelling patterns. The clinical problem is the analysis of the impact of two different surgical palliation techniques for hypoplastic left heart syndrome. Construction of a computational atlas and the statistical description of its variability are performed from the short axis stack of 128 subjects. Results unveil, for the first time in the literature, the differences in remodelling of the systemic right ventricle depending on the surgical palliation technique.</p

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Revealing differences in anatomical remodelling of the systemic right ventricle

Revealing differences in anatomical remodelling of the systemic right ventricle

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