Background: Tuberculosis (TB) is a major concern among high-risk populations such as the homeless. Tuberculosis (TB) is a major public health problem. The Chennai City has a large population of homeless persons and caregivers and is estimated to be the largest TB-endemic area in the intermediate-prevalence country, India. However, there have been few studies of homeless persons and caregivers. The objective of this study to assess the prevalence and risk factors for pulmonary TB among homeless population around Chennai. Methods: We conducted a cross-sectional study for screening TB symptoms using questionnaire. The study participants were recruited from 15 zones, which included 47-night shelters around Chennai under the control of the Chennai City in Tamil Nadu. Data was collected from homeless people who were living in night shelters in the northern, central, and southern regions of Chennai City. Results: Complete responses were available from 484 individuals (263 homeless persons and 173 caregivers). Four active TB cases (1.5%) among homeless persons were found, while there were no cases among caregivers
