Retinol level in patients with psoriasis during treatment with B group vitamins, a bacterial polysaccharide (pyrogenal) and methotrexate (Russian)

Abstract

A study of 160 patients with psoriasis revealed a reduction in the content of vitamin A in patients with various forms of psoriasis. During treatment with group B vitamins the best therapeutic effect was observed with vitamins B5 and B15. An increase of vitamin A in the blood was noted during treatment with vitamins B2 and pellagra preventive factor, whereas vitamins B1, B5, B6, B9, B12 and B15 caused a decline of the vitamin A level in the blood. During treatment of psoriatic patients with pyrogenal the content of vitamin A in the blood increased, while methotrexate therapy caused it to decrease. Vitamin A appears to be effective in the treatment of various forms of psoriasis both alone and in combination with methotrexate and vitamins B1, B5, B6, B9, B12 and B15