Steroid Non-Responsive Optic Neuropathy (Presentation Video)

Abstract

Loss of vision OUA 75-year old with painless, progressive loss of vision. Previous history significant for BPH and excised skin malignant melanoma.VA: Initial - 20/50 OD, 20/25 OS; Color plates: 6/12 OD, 12/12 OS; Follow-up - 20/70 OD, 20/120 OS; Color plates: 1/12 OD, 0/12 OS; RAPD OSMRIGlomeruloid vascular proliferation; Cells positive for glial fibrillary astrocytic protein consistent with glioblastoma multiforme.Corticosteroids; Surgery; XRT1. Millar WS, Tartaglino LM, Sergott RC, Freidman DP and Flanders AE: MR of Malignant Optic Glioma of Adulthood. AJNR 16:1673-1676, 1995. 2. Freidman DP and Hollander MD: Neuroradiology Case of the Day. RadioGraphics 18: 1046-1048, 1998. 3. Wabbels B, Demmler A, Seitz J et al: Unilateral adult malignant optic nerve glioma. Graefe's Arch Clin Exp Ophthalmol 242:741-748, 2004. 4. Hoyt WF, Meshel LG, Lessell S and al:Malignant Optic Glioma of Adulthood. Brain 96: 121-132, 1973