ZEBRAFISH: AN EMERGING MODEL SYSTEM FOR DRUG DISCOVERY

Abstract

ABSTRACTThe zebrafish is no doubt a powerful model organism with a combination of forward and reverse genetics, low cost, amenable high throughput, andrapid in vivo analysis. With these unique features, it can be expected that the zebrafish will become more frequently used for drug discovery. Thisreview outlines the potential of zebrafish to contribute to drug discovery through the identification of novel drug targets, validation of those targetsand screening for new therapeutic compounds and assay development.Keywords: Zebrafish, Drug screening, Drug target, Development

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