This article briefly outlines three examples of cross-cultural academic programs, each bringing to the table either indigenous knowledge or Chinese medicine, knowledge generally considered to lie beyond the research base of 1862 land-grant institutions. In the process, the gate-keeping function of our research-base is challenged, examined here through a cultural lens. Including diverse ways of knowing as assets within the scope of academic work can enhance engagement outreach, but it asks us to re-examine basic assumptions of our academic culture