A device for obtaining threedimensional
cell cultures comprising: a sub
strate (1); a plurality of micro-structures (2)
which protrude from the surface of the sub
strate (1) and are arranged on such substrate
(1) according to a periodical grid so as to
make the substrate (1) super hydrophobic. The
device is characterised in that the micro-struc
tures (2) have side walls at least partially
nano-patterned and have projections (14) and
recesses (16) alternated with a predetermined
distance