Introduction: Dry eye is a multifactorial ocular surface disease characterized by symptoms of discomfort, irritation, and visual disturbance. The symptoms of dry eye can be correlated to Shushkakshipaka which is one among the Sarvagata Netra Rogas affecting all parts of the eye as explained in classical Ayurveda texts. Here the patient presenting with signs and symptoms of dry eye disease was treated according to the treatment principles of Shushkakshipaka as explained in Ayurvedic classics. Yashtimadhu Ksheerapaka Tarpana was selected for the treatment and the same has been presented in the article. Materials and Methods: The subject who approached Shalakya Tantra OPD of Sri Jayachamarajendra Institute of Indian Medicine Hospital, Bengaluru, with signs and symptoms of dry eye disease like dryness in both the eyes, foreign body sensation, burning sensation and blurred vision etc. was thoroughly examined and systematically reviewed and treatment was planned based on the Chikitsasutra of Shushkakshipaka. Result: The patient showed considerable improvement subjectively and objectively. Improvement in schirmers reading, visual acuity improvement was observed in both eyes. Discussion: The maintenance of stability of tear film is the main challenge in the present scenario. This can be achieved by properly following the treatment principle and protocol during and after the treatment for the prescribed period
