Alice Giotta Lucifero

Sabino Luzzi

English

Archivio Istituzionale della Ricerca - Università degli Studi di Pavia

1   ComposeLabelsMoreInbox 16StarredSnoozedSentDrafts 1[Gmail]All Mail[Gmail]TrashScopusto me wfns2021@bcocongresos.com via mail.eventsairmail.com  Oct 12, 2021, 3:39 PMto meWFNS 2022ID (Ref. number): 791Full name: Sabino LuzziCity: PaviaCountry: ItalyEmail: sabino.luzzi@unipv.it, Dear Dr. Sabino Luzzi,Thank you for submitting your abstract for the XVII World Congress ofNeurosurgery (WFNS 2022), which will be held March 13-18, 2022, in theConvention Center Ágora Bogotá (Colombia), We acknowledge receipt of the following information. Submitted Abstract Title Supratentorial High-Grade Gliomas: Maximal SafeAnatomical Resection Guided by AugmentedReality High-Definition Fiber Tractography andFluoresceinPaper Number 1117Paper Status SentPresentation Type OralTheme OncologyAbstract Body Objective: The theoretical advantages ofaugmented reality (AR) with diffusion tensorimaging (DTI)–based high- definition fibertractography (HDFT) and sodium fluorescein (F) inhigh-grade glioma (HGG) surgery have not beeninvestigated in detail. In this study, the authorsaimed to evaluate the safety and efficacy profilesof HDFT-F microscope-based AR cytoreductivesurgery for newly diagnosed supratentorial HGGs.Methods: Data of patients with newly diagnosedsupratentorial HGGs who underwent surgery usingthe AR HDFT- F technique were reviewed andcompared with those of a cohort of patients whounderwent conventional white-light surgeryassisted by infrared neuronavigation. The safetyand efficacy of the techniques were reported basedon the postoperative Neurological Assessment inNeuro-Oncology (NANO) scores, the extent ofresection (EOR), and Kaplan-Mei- er curves,respectively. The chi-square test was conducted forcategorical variables. A p-value < 0.05 wasconsidered statistically significant. Results: A totalof 54 patients underwent surgery using the ARHDFT-F technique, and 63 underwentconventional white-light surgery assisted byinfrared neuronavigation. The mean postoperativeNANO scores were 3.8 ± 2 and 5.2 ± 4 in the ARHDFT-F group and control group, respectively (p <0.05). The EOR was higher in the AR HDFT-Fgroup (p < 0.05) than in the control group. With amean follow-up of 12.2 months, the rate ofprogression-free survival (PFS) was longer in thestudy group (log-rank test, p = 0.006) than in thecontrol group. Moreover, the complication rateswere 9.2% and 9.5% in the study and controlgroups, respectively. Conclusions: Overall, ARHDFT-F–assisted surgery is safe and effective inmaximizing the EOR and PFS rate for patients withnewly diagnosed supratentorial HGGs, and inoptimizing patient functional outcomes.Presenting Author Dr. Sabino LuzziAffiliations: Neurosurgery Unit, Department ofClinical-Surgical, Diagnostic and PediatricSciences, University of PaviaCo-Author Dr. Alice Giotta Lucifero24 of 26MailChatSpacesMeet16ActiveWFNS 2022 

Supratentorial High-Grade Gliomas: Maximal Safe Anatomical Resection Guided by Augmented Reality High-Definition Fiber Tractography and Fluorescein

https://iris.unipv.it/bitstream/11571/1465260/1/Supratentorial%20High-Grade%20Gliomas-%20Maximal%20Safe%20Anatomical%20Resection%20Guided%20by%20Augmented%20Reality%20High-Definition%20Fiber%20Tractography%20and%20Fluorescein.pdf

Supratentorial High-Grade Gliomas: Maximal Safe Anatomical Resection Guided by Augmented Reality High-Definition Fiber Tractography and Fluorescein

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Archivio Istituzionale della Ricerca - Università degli Studi di Pavia