Study of dyslipidemia in patients with Obstructive Sleep Apnea Syndrome in primary health care

Abstract

Background. Obstructve Sleep Apnea Syndrome (OSAS) is associated with several morbidites. The most important ones are obesity, hypertension and diabetes mellitus. A clear relatonship of OSAS and dyslipidemia is yet to be demonstrated. Objectves. To evaluate the prevalence of dyslipidemia as a morbidity associated with OSAS and to understand its relatonship with the severity of OSAS. Material and methods. We randomly selected 92 patents diagnosed untl the end of May 2016 with OSAS from two primary health care units and 184 patents as controls (no OSAS diagnosed) from random lists of patents matched in age and gender with patents with OSAS. We calculated the prevalence of the classifed comorbidites (overweight, hypertension, type 2 diabetes mellitus and dyslipidemia) in both groups. We used logistc regression to check the associaton between them. We evaluated the relatonship between dyslipidemia and OSAS severity by using the Apnea/Hypopnea Index (AHI). Results. The prevalence of dyslipidemia was 80% in patents with OSAS. Patents with OSAS were diagnosed as overweight (97%), had arterial hypertension (89%) and type 2 diabetes mellitus (43%). OSAS was not independently related to type 2 diabetes mellitus (p = 0.101) and to dyslipidemia (p = 0.389). However, overweight and arterial hypertension were related independently to OSAS (p < 0.001) with a risk for OSAS. The prevalence of dyslipidemia in patents with mild, moderate and severe OSAS was 22%, 13% and 25%, respectvely. Conclusions. Patents with OSAS have a high prevalence of dyslipidemia despite not being independently related. There were no statstcal differences between patents with mild, moderate and severe OSAS.info:eu-repo/semantics/publishedVersio

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