Deteksi Zat Anti Skizon Plasmodium Falciparum dengan Elisa: (suatu Penelitian Pendahuluan)

Abstract

A preliminary study based on ELISA was done to evaluate anti-malarial antibodies on 35 persons living in a hypoendemic area, Wonosobo, Central Java. Schizonts of Plas­modium falciparum strain Flores cultured in vitro were extracted and used as antigen. As negative controls, 27 sera were drawn from British persons who had never been visiting endemic area. The result showed that 20% (7/35) of the sample contained anti-malaria antibodies, however, by using chi-square test and Yate's correction it was shown that there was no significant difference between group of persons with parasite and/or splenomegaly compared to group of persons without parasite and without splenomegaly (p > 0.05)