Apers, Thomas

Bracke, Bart

Chapelle, Thiery

Hartman, Vera

Hendrikx, Bart

op de Beeck, Bart

Roeyen, Geert

Ysebaert, Dirk

Abstract: Background Hepatectomy remains the most important treatment modality for most malignant liver tumors. Vascular involvement stays a reason for unresectability or major parenchymal resection. A possible way to avoid this is parenchymal-sparing hepatectomy (PSHX) with vascular resection and reconstruction (HVRR). In this article, we aim to demonstrate the specific role of this technique in avoiding post-hepatectomy liver failure (PHLF). Methods A retrospective analysis of 10 patients who underwent HVRR was conducted. (99m)Technetium-mebrofenin hepatobiliary scintigraphy (HBS) was used to predict the future liver remnant function (FLRF). Calculations were made for each patient to compare HVRR and major hepatectomy (with or without portal vein embolization). Results In our cohort, there was no perioperative mortality. Two patients suffered a Clavien-Dindo grade 3a complication and none had clinically significant PHLF. Estimated FLRF was significantly higher in HVRR compared to major hepatectomy after portal vein embolization (p < .005). Conclusions Instead of focusing on inducing liver remnant hypertrophy, preserving parenchyma through HVRR can be an interesting treatment strategy. It can be performed with an acceptable operative risk. Calculations of FLRF (using HBS) suggest that this approach is able to reduce the risk for PHLF and related morbidity or mortality

Institutional Repository Universiteit Antwerpen

Parenchymal-sparing hepatectomy with hepatic vein resection and reconstruction

Parenchymal-sparing hepatectomy with hepatic vein resection and reconstruction

Abstract

Similar works

Full text

Available Versions

Institutional Repository Universiteit Antwerpen